
Assessment of Proarrhythmic Adverse Effects during Drug Development: Current Status and Challenges Ahead
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Chair(s):
Jules Hancox,
Professor of Cardiac Electrophysiology,School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, United KingdomPaul Volders,
Cardiologist and Principal Investigator,Department of Cardiology, CARIM, Maastricht University Medical Center, Maastricht, The Netherlands -
Session description:
Mechanisms of drug-induced arrhythmia: implications for cardiac safety evaluation of drugs in development
Professor Jules Hancox
Professor of Cardiac Electrophysiology, School of Physiology, Pharmacology and Neuroscience, University of Bristol, United KingdomCurrent approaches to the assessment of proarrhythmic potential of drugs and surrogate parameters of drug-induced arrhythmia
Professor Paul Volders
Cardiologist and Principal Investigator, Department of Cardiology, CARIM, Maastricht University Medical Center, Maastricht, The NetherlandsOral communication speaker - to be confirmed in 2023.
Evaluation of the hidden cardiotoxic effects of COX2 inhibitors
Dr Gabor Brenner
Department of Pharmacology and Pharmacotherapy, Semmelweis University Hungary, Budapest,
HungaryTransgenic Rabbit Models for Proarrhythmia Prediction
Professor Katja Odening
Department of Cardiology and Angiology I, Heart Center, University of Freiburg Germany, Freiburg,
Germany
Department of Physiology, University of Bern, Bern, Switzerland
Speakers
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Dr Gabor BrennerDepartment of Pharmacology and Pharmacotherapy, Semmelweis University Hungary, Budapest, Hungary
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Professor Jules HancoxProfessor of Cardiac Electrophysiology, School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, United Kingdom
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Professor Katja OdeningDepartment of Cardiology and Angiology I, Heart Center, University of Freiburg, Freiburg, Germany; Department of Physiology, University of Bern, Bern, Switzerland
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Professor Paul VoldersCardiologist and Principal Investigator, Department of Cardiology, CARIM, Maastricht University Medical Center, Maastricht, The Netherlands
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