Neuropharmacology session icon

Addressing the challenges in translational pharmacology through academic-industrial collaboration

  • Chair(s):

    Sophie Bradley
    Senior Lecturer, University of Glasgow, Glasgow, United Kingdom

    Brian Hudson
    Lecturer, University of Glasgow, Glasgow, United Kingdom

  • Session description:

    G protein-coupled receptors (GPCR) regulate almost every (patho)physiological process and are the most intensively studied drug targets.  Approximately 27% of non-olfactory GPCRs have been successfully targeted in the clinic.  However, there remains more than 50% of non-olfactory GPCR subtypes that are yet to be explored in clinical trials, indicating that the promise held by GPCR targets in drug discovery is yet to be fully realised.  The challenge for translational pharmacology is to understand the molecular mechanisms underlying drug efficacy in the context of human diseases in order to inform the rational design of GPCR therapies and to improve the translation of drug candidates to practise.  This symposium aims to illustrate how academic and industrial partnerships are addressing this challenge, by working in collaboration to exploit novel GPCR targets for the treatment of human diseases.
    This symposium will include 4 "pairs" of academic-industrial speakers:

    Talk title to be confirmed
    Dr Chris Langmead
    Monash Institute for Pharmaceutical Sciences, Australia

    Apelin receptor atomic structure and pharmacology of novel ligands
    Dr Janet Maguire
    College Lecturer in Medicine, Queen's College Cambridge, United Kingdom
    Dr Alastair Brown

    Oral communication speaker - to be confirmed in 2023.

    Talk title to be confirmed
    Professor Jan Steyaert
    Vrije Universiteit, Brussel
    Christel Menet
    Confo Therapeutics

    Talk title to be confirmed
    Professor Graeme Milligan
    University of Glasgow, United Kingdom
    Dr Vera Nies
    Programme Manager at Foundation Lygature, and Charity Programme Lead at the European Lead Factory


03 Jul 2023


9:45 am - 12:10 pm


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